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Howard A Burris Selected Research

Drug Therapy (Chemotherapy)

11/2023A randomized phase II study of metronomic cyclophosphamide and methotrexate (CM) with or without bevacizumab in patients with advanced breast cancer.
1/2023Efficacy and safety of rucaparib treatment in patients with BRCA-mutated, relapsed ovarian cancer: final results from Study 10.
1/2021Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study.
5/2016Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.
1/2016A phase II trial of bevacizumab and everolimus as treatment for patients with refractory, progressive intracranial meningioma.
7/2015Combination of everolimus with trastuzumab plus paclitaxel as first-line treatment for patients with HER2-positive advanced breast cancer (BOLERO-1): a phase 3, randomised, double-blind, multicentre trial.
2/2014A first-in-human dose-escalation study of ME-143, a second generation NADH oxidase inhibitor, in patients with advanced solid tumors.
8/2013An integrated multiple-analyte pharmacokinetic model to characterize trastuzumab emtansine (T-DM1) clearance pathways and to evaluate reduced pharmacokinetic sampling in patients with HER2-positive metastatic breast cancer.
1/2013Developments in the use of antibody-drug conjugates.
8/2012Phase II study of maintenance sunitinib following irinotecan and carboplatin as first-line treatment for patients with extensive-stage small-cell lung cancer.
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Howard A Burris Research Topics

Disease

117Neoplasms (Cancer)
01/2024 - 01/2002
66Breast Neoplasms (Breast Cancer)
01/2024 - 01/2002
25Neutropenia
01/2023 - 05/2003
21Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 05/2005
17Disease Progression
05/2024 - 04/2003
16Thrombocytopenia (Thrombopenia)
10/2019 - 02/2002
16Diarrhea
01/2019 - 05/2003
14Carcinoma (Carcinomatosis)
12/2021 - 03/2002
13Fatigue
01/2019 - 12/2007
13Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2018 - 05/2002
10Nausea
01/2018 - 11/2005
9Vomiting
01/2019 - 11/2005
9Neoplasm Metastasis (Metastasis)
03/2016 - 04/2008
8Exanthema (Rash)
01/2019 - 12/2007
8Febrile Neutropenia
01/2018 - 02/2002
8Colorectal Neoplasms (Colorectal Cancer)
05/2015 - 08/2007
7Anemia
01/2018 - 06/2010
6Ovarian Neoplasms (Ovarian Cancer)
01/2023 - 05/2010
5Mucositis
10/2017 - 05/2009
5Melanoma (Melanoma, Malignant)
03/2016 - 09/2010
4Renal Cell Carcinoma (Grawitz Tumor)
11/2020 - 12/2007
4Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2018 - 10/2002
4Infections
01/2018 - 10/2011
4Prostatic Neoplasms (Prostate Cancer)
08/2017 - 03/2007
4Stomatitis
02/2017 - 02/2012
4Fever (Fevers)
01/2017 - 10/2008
4Pancreatic Neoplasms (Pancreatic Cancer)
04/2013 - 03/2005
3Hyperglycemia
01/2024 - 02/2012
3Lymphoma (Lymphomas)
01/2023 - 03/2007
3Pain (Aches)
08/2018 - 09/2015

Drug/Important Bio-Agent (IBA)

26Carboplatin (JM8)FDA LinkGeneric
12/2019 - 03/2002
22Paclitaxel (Taxol)FDA LinkGeneric
08/2017 - 01/2002
21Hormones (Hormone)IBA
12/2023 - 03/2010
21Trastuzumab (Herceptin)FDA Link
10/2023 - 01/2004
18EverolimusFDA Link
12/2023 - 04/2008
18Bevacizumab (Avastin)FDA Link
11/2023 - 12/2007
17GemcitabineFDA Link
05/2024 - 03/2002
14Ado-Trastuzumab EmtansineIBA
11/2019 - 06/2010
14Docetaxel (Taxotere)FDA Link
01/2017 - 05/2005
12ErbB Receptors (EGF Receptor)IBA
10/2023 - 08/2005
11exemestane (Aromasin)FDA Link
12/2023 - 02/2012
11Irinotecan (Camptosar)FDA LinkGeneric
01/2015 - 05/2003
10taxaneIBA
11/2019 - 01/2002
9PlatinumIBA
01/2023 - 02/2002
9Aromatase InhibitorsIBA
01/2021 - 02/2012
9Immunoconjugates (Immunoconjugate)IBA
01/2020 - 06/2010
9Pemetrexed (MTA)FDA Link
12/2019 - 01/2010
8Biomarkers (Surrogate Marker)IBA
11/2023 - 08/2013
8human ERBB2 proteinIBA
10/2023 - 02/2011
8Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2018 - 12/2007
7Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2023 - 06/2008
7Angiogenesis InhibitorsIBA
11/2023 - 01/2010
7pertuzumabIBA
10/2023 - 09/2012
7Doxorubicin (Adriamycin)FDA LinkGeneric
08/2017 - 06/2008
7ixabepilone (BMS 247550)FDA Link
08/2017 - 03/2007
7Monoclonal AntibodiesIBA
04/2013 - 03/2010
6Epidermal Growth Factor (EGF)IBA
12/2023 - 05/2010
6pegfilgrastim (Neulasta)FDA Link
01/2018 - 06/2008
6Capecitabine (Xeloda)FDA Link
02/2014 - 01/2010
6Lapatinib (GW572016)FDA Link
06/2011 - 01/2004
6Topotecan (Hycamtin)FDA LinkGeneric
05/2011 - 05/2002
5Fulvestrant (Faslodex)FDA Link
01/2024 - 06/2011
5Letrozole (Femara)FDA LinkGeneric
10/2022 - 11/2016
5ribociclibIBA
10/2022 - 11/2016
5Estrogen ReceptorsIBA
01/2020 - 05/2013
5pazopanibFDA Link
01/2018 - 01/2010
5TOR Serine-Threonine KinasesIBA
01/2016 - 04/2008
5Epothilones (Epothilone)IBA
10/2012 - 03/2007
4Immune Checkpoint InhibitorsIBA
05/2024 - 05/2016
4Proteins (Proteins, Gene)FDA Link
01/2024 - 04/2006
4Phosphotransferases (Kinase)IBA
01/2024 - 01/2004
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2023 - 06/2011
4rucaparibIBA
01/2023 - 08/2017
4atezolizumabIBA
01/2022 - 11/2014
4Sorafenib (BAY 43-9006)FDA Link
11/2017 - 05/2010
4Aspartate Aminotransferases (Aspartate Transaminase)IBA
08/2017 - 05/2011
4dabrafenibIBA
03/2016 - 11/2012
4trametinibIBA
03/2016 - 08/2012
4AnthracyclinesIBA
12/2014 - 04/2009
4Fluorouracil (Carac)FDA LinkGeneric
07/2012 - 01/2002
4Cetuximab (Erbitux)FDA Link
07/2010 - 08/2007
4Vinorelbine (Navelbine)FDA LinkGeneric
08/2009 - 04/2003
3AlpelisibIBA
01/2024 - 01/2018
3Tyrosine (L-Tyrosine)FDA Link
01/2023 - 01/2004
3AndrogensIBA
01/2022 - 03/2007
3Poly(ADP-ribose) Polymerase InhibitorsIBA
12/2021 - 08/2017
3Anastrozole (Arimidex)FDA LinkGeneric
01/2021 - 06/2011
3Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2021 - 11/2016
3Mechanistic Target of Rapamycin Complex 1IBA
11/2020 - 04/2013
3Messenger RNA (mRNA)IBA
12/2019 - 04/2013
3Tumor Biomarkers (Tumor Markers)IBA
11/2019 - 01/2019
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2019 - 10/2017

Therapy/Procedure

62Therapeutics
12/2023 - 07/2002
29Drug Therapy (Chemotherapy)
11/2023 - 07/2002
7Radiotherapy
01/2016 - 07/2002
6Neoadjuvant Therapy
11/2015 - 06/2008
4Immunotherapy
11/2023 - 09/2010
4Combination Drug Therapy (Combination Chemotherapy)
01/2018 - 03/2002
4Aftercare (After-Treatment)
01/2016 - 05/2010
3Intravenous Infusions
01/2020 - 11/2010